ChAsE: Chromatin analysis and exploration tool

ChAsE: Chromatin analysis and exploration tool

Abstract

Summary: We present ChAsE, a cross-platform desktop application developed for interactive visualization, exploration and clustering of epigenomic data such as ChIP-seq experiments. ChAsE is designed and developed in close collaboration with several groups of biologists and bioinformaticians with a focus on usability and interactivity. Data can be analyzed through k-means clustering, specifying presence or absence of signal in epigenetic data, and performing set operations between clusters. Results can be explored in an interactive heat map and profile plot interface and exported for downstream analysis or as high quality figures suitable for publications. Availability: Software, source code (MIT License), data, and video tutorials available at http://chase.cs.univie.ac.at . Contact: mkarimi@brc.ubc.ca

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Authors
  • Younesy, Hamid
  • Nielsen, Cydney B.
  • Lorincz, Matthew C.
  • Jones, Steven J.M.
  • Karimi, Mohammad M.
  • Möller, Torsten
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Supplemental Material
Shortfacts
Category
Journal Paper
Divisions
Visualization and Data Analysis
Journal or Publication Title
Bioinformatics
ISSN
1367-4803
Number
btw382
Date
July 2016
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