Functional RNA Structures in the 3'UTR of Mosquito-Borne Flaviviruses

Functional RNA Structures in the 3'UTR of Mosquito-Borne Flaviviruses

Abstract

Recent experimental evidence revealed a thorough understanding of the involvement of func-tional RNA elements in the 3’ untranslated regions (UTRs) of flaviviruses with virus tropism. Comparative genomics and thermodynamic modelling allow for the prediction and functional characterization of homologous structures in phylogenetically related viruses. We provide here a comprehensive overview of evolutionarily conserved RNAs in the 3’UTRs of mosquito-borne flaviviruses.

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Authors
  • Wolfinger, Michael T.
  • Ochsenreiter, Roman
  • Hofacker, Ivo L.
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Editors
  • Frishman, Dmitrij
  • Marz, Manja
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Shortfacts
Category
Book Section/Chapter
Divisions
Bioinformatics and Computational Biology
Title of Book
Virus Bioinformatics
ISSN/ISBN
9781003097679
Page Range
pp. 65-100
Date
19 August 2021
Official URL
https://www.taylorfrancis.com/chapters/edit/10.120...
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